On successful completion of this course, you will be able to:
- Identify how carbohydrates are broken down
1. Brief account on the occurrence of carbohydrates, structure, properties and
biological importance (monosaccharides, disaccharides and polysaccharides
1. Breakdown of carbohydrates: digestion and absorption of carbohydrate, breakdown of
glycogen, Starch and disaccharides.
2. Glycolysis: entry of other carbohydrates into the glycolytic sequences, alcoholic
fermentation, regulation of glycolysis.
3. Citric acid cycle: establishment of the cyclic nature, individual reactions and enzymes of
citric acid cycle. Amphibolic nature of the cycle.
4. Glyoxylate cycle. Control of citric acid cycle.
5. Pentose phosphate pathway of glucose oxidation. Importance of the pathway and its
6. Biosynthesis: biosynthesis of glucose from non-carbohydrate precursors
(gluconeogenesis). Control of gluconeogenesis. Glycogen synthesis and its regulation,
7. Role of nucleoside diphosphate sugars in carbohydrate biosynthesis and in sugar inter
8. Glycoprotein biosynthesis
B. Lipid Metabolism:
1. Digestion and absorption of triglycerides, phospholipids, glycolipids and sterols.
2. Biosynthesis of saturated, unsaturated, hydoxy and branched chain fatty acids.
3. Oxidation of fatty acids and different pathways for such oxidation. Biosynthesis and
degradation of phospholipids.
4. Glycolipids. Sterol biosynthesis and conversion of cholesterol to various other
biologically important compounds.
5. Formation of prostaglandins, prostacyclins and thromboxanes from unsaturated fatty
6. Regulation of the various synthetic and degradative processes mentioned above.
Go beyond the readings prescribed for the course
Attend & participate in all the discussions in the class
Be original in all your assignments and submit them on time
Late submissions will attract downgrading of 10%/day
You will complete three assignments (mandatory): 60 marks
End-semester examination: 40 marks
Assignments & deadlines will be announced in the class